ACE2-GFP Expressing Human Pulmonary Artery Endothelial Cells
BVX-0120ACE2-GFP
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IncludedProduct Details
Size
1ml
Product Code
BVX-0120ACE2-GFP
Quick Specifications
- Product Type: Human Endothelial Cells
- Storage: 37°C, 5% CO?, humidified atmosphere.
- Catalog: BVX-0120ACE2-GFP
ACE2-GFP Expressing Human Pulmonary Artery Endothelial Cells
Product Description
ACE2-GFP Expressing Human Pulmonary Artery Endothelial Cells are genetically engineered primary human pulmonary artery endothelial cells that stably express ACE2 (Angiotensin-Converting Enzyme 2) fused or co-expressed with GFP (Green Fluorescent Protein). These cells provide a reliable in vitro model for studying pulmonary vascular biology, ACE2-mediated signaling pathways, viral entry mechanisms, endothelial dysfunction, inflammation, and cardiovascular or respiratory disease research. GFP expression enables convenient real-time visualization, cell tracking, imaging, and transfection monitoring.
These specialized endothelial cells maintain key endothelial characteristics such as cobblestone morphology, marker expression, and functional responsiveness under optimized culture conditions. They are valuable tools for research involving SARS-CoV-2 host interaction studies, lung injury models, vascular permeability, angiogenesis, and therapeutic screeningACE2-GFP Expressing Human Pulmonary Artery Endothelial Cells are genetically engineered primary human pulmonary artery endothelial cells that stably express ACE2 (Angiotensin-Converting Enzyme 2) fused with GFP (Green Fluorescent Protein). These cells serve as a reliable in vitro model for studying various aspects of pulmonary vascular biology, including ACE2-mediated signaling pathways, viral entry mechanisms, endothelial dysfunction, inflammation, and research related to cardiovascular or respiratory diseases. The expression of GFP allows for convenient real-time visualization, cell tracking, imaging, and monitoring of transfection.
Key Features & Benefits
- Cell Type: Human Pulmonary Artery Endothelial Cells (HPAECs)
- Genetic Modification: ACE2-GFP expressing
Species: Human
- Morphology: Typical endothelial cobblestone morphology
- Marker Expression: CD31, VE-Cadherin, vWF, eNOS (expected endothelial markers)
- Reporter: Green Fluorescent Protein (GFP)
- Growth Properties: Adherent monolayer culture
- Passage Number: Low passage recommended
- Storage Format: Cryopreserved vial
- Viability Post-Thaw: High viability under validated thaw protocol
- Recommended Medium: Endothelial Cell Growth Medium
- Quality Control: Sterility, mycoplasma negative, viability tested
Quick Facts
Product Type
Human Endothelial Cells
Viability
High viability
Storage
37°C, 5% CO?, humidified atmosphere.
Shelf Life
Long-term
Applications
Technical Specifications
| Product Type | Human Endothelial Cells |
|---|---|
| Storage Conditions | 37°C, 5% CO?, humidified atmosphere. |
| Product Code | BVX-0120ACE2-GFP |
| Size/Format | 1ml |
| Category | Primary Cells |
Primary Applications
Applications & Use Cases
Primary Applications
- ACE2 receptor biology studies - SARS-CoV-2 spike protein binding and entry research - Pulmonary vascular disease modeling - Endothelial dysfunction studies - Lung inflammation research - Drug discovery and antiviral screening - GFP live-cell imaging and fluorescence microscopy - Signal transduction analysis - Vascular permeability assays - Gene expression and pathway studies - Cell migration and angiogenesis assays - Toxicology testing
Suitable for - ace2 receptor biology studies - sars-cov-2 spike protein binding and entry research - pulmonary vascular disease modeling - endothelial dysfunction studies - lung inflammation research - drug discovery and antiviral screening - gfp live-cell imaging and fluorescence microscopy - signal transduction analysis - vascular permeability assays - gene expression and pathway studies - cell migration and angiogenesis assays - toxicology testing studies and research applications
Research Use Cases
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Technical Support & Documentation
Technical Support
Our experts are available for technical questions and protocol assistance.
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