Human Brain Microvascular Endothelial Cells (HBMVECs)
BVX-0002
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IncludedProduct Details
Size
1ml
Product Code
BVX-0002
Quick Specifications
- Product Type: Human Endothelial cells
- Viability: >95% viable (Trypan Blue exclusion)
- Storage: Store in liquid nitrogen vapor phase (-196°C) for long-term. Ship on dry ice (-80°C).
- Shelf Life: Very stable in the Liquid Nitrogen Vapor Phase
- Catalog: BVX-0002
- Growth: Primary cells capable of multiple passages when using recommended medium and proper handling
Human Brain Microvascular Endothelial Cells (HBMVECs)
Product Description
Human Brain Microvascular Endothelial Cells are primary endothelial cells isolated from the microvasculature of human brain tissue. These cells are key structural components of the blood-brain barrier (BBB) and regulate selective permeability, nutrient transport, neurovascular signaling, and central nervous system homeostasis. They display characteristic endothelial cobblestone morphology and grow as adherent monolayers under optimized culture conditions.
These cells are widely used in neuroscience research, BBB models, neuroinflammation studies, drug transport screening, stroke research, and neurovascular disease investigations.Human brain microvascular endothelial cells are primary endothelial cells isolated from the microvasculature of human brain tissue. These cells are crucial structural components of the blood-brain barrier (BBB) and play a key role in regulating selective permeability, nutrient transport, neurovascular signaling, and maintaining homeostasis in the central nervous system. They exhibit a characteristic cobblestone morphology and grow as adherent monolayers under optimized culture conditions.
These cells are widely utilized in neuroscience research, models of the blood-brain barrier, studies on neuroinflammation, drug transport screening, stroke research, and investigations into neurovascular diseases.Human brain microvascular endothelial cells are primary endothelial cells isolated from the microvasculature of human brain tissue. These cells are crucial structural components of the blood-brain barrier (BBB) and play a key role in regulating selective permeability, nutrient transport, neurovascular signaling, and maintaining homeostasis in the central nervous system. They exhibit a characteristic cobblestone morphology and grow as adherent monolayers under optimized culture conditions.
These cells are widely utilized in neuroscience research, models of the blood-brain barrier, studies on neuroinflammation, drug transport screening, stroke research, and investigations into neurovascular diseases.
Key Features & Benefits
- Cell Type: Human Brain Microvascular Endothelial Cells
- Species: Human
- Tissue Origin: Brain microvasculature
- Morphology: Typical endothelial cobblestone morphology
- Growth Characteristics: Adherent monolayer culture
- Physiological Role: Blood-brain barrier component
- Recommended Medium: Endothelial Cell Growth Medium
- Cryopreservation Format: Frozen vial
- Viability: High post-thaw viability
- Markers: CD31, VE-Cadherin, vWF, GLUT1, Claudin-5, Occludin
- Quality Control: Sterility tested, mycoplasma negative, identity verified
- Passage: Low passage recommended
Quick Facts
Product Type
Human Endothelial cells
Viability
>95% viable (Trypan Blue exclusion)
Storage
Store in liquid nitrogen vapor phase (-196°C) for long-term. Ship on dry ice (-80°C).
Shelf Life
Very stable in the Liquid Nitrogen Vapor Phase
Applications
Technical Specifications
| Product Type | Human Endothelial cells |
|---|---|
| Viability | >95% viable (Trypan Blue exclusion) |
| Proliferative Capability | Primary cells capable of multiple passages when using recommended medium and proper handling |
| Storage Conditions | Store in liquid nitrogen vapor phase (-196°C) for long-term. Ship on dry ice (-80°C). |
| Shelf Life | Very stable in the Liquid Nitrogen Vapor Phase |
| Product Code | BVX-0002 |
| Size/Format | 1ml |
| Category | Primary Cells |
Primary Applications
Applications & Use Cases
Primary Applications
- Blood-brain barrier studies - CNS drug permeability screening - Neuroinflammation research - Stroke and ischemia models - Neurovascular signaling studies - Cell migration and proliferation assays - Toxicology testing - Brain metastasis research - Co-culture neuron/glia BBB models - Tissue engineering and regenerative medicine
Suitable for - blood-brain barrier studies - cns drug permeability screening - neuroinflammation research - stroke and ischemia models - neurovascular signaling studies - cell migration and proliferation assays - toxicology testing - brain metastasis research - co-culture neuron/glia bbb models - tissue engineering and regenerative medicine studies and research applications
Research Use Cases
In Vitro Studies
Cell culture and screening applications
Molecular Biology
Gene expression & signaling studies
Drug Discovery
Screening & validation studies
Technical Support & Documentation
Technical Support
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